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Multidimensional Phenotyping Towards Personalized Preventive Nutritional Support for Elderly People

Study acronym: MetabotypAGE
StatusRecruiting
PhaseNot applicable
Started
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Record status
This record was last updated March 27, 2026 (before its estimated June 30, 2026 completion). Its status may not reflect the trial's current state.

Record History

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  1. Secondary endpoints: 28 to 30v6
  2. Phase: Not specified to Not applicablev5 Show 7 more changesShow less
    • Enrollment target: 150 to 250
    • Primary completion date: Dec 2025 to Jun 30, 2026
    • Study completion date: Mar 2026 to Mar 2027
    • Site details revised at 2 of 3 sites
    • Publications: details revised at 3 of 6 entries
    • Study arms: 0 to 1
    • Study description shortened, about 1 word
  3. Site details revised at 1 of 3 sites
    • Publications: details revised at 3 of 6 entries
    v4
  4. Start date changed from estimate of Feb 2024 to Feb 14, 2024v3
  5. Trial status: Not Yet Recruiting to Recruiting
    • Start date: Dec 2023 to Feb 2024
    • Site details revised at 3 of 3 sites
    v2
  6. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
There is high inter-individual variability in the response to feeding, which is determined by multiple interacting factors such as age, sex, genotype, gut microbiota, eating behaviors, physical activity or even socio-demographic factors. Original studies have recently demonstrated the possibility of predicting the postprandial response to the diet of healthy individuals on the basis of in-depth phenotyping, and of offering them foods adapted to their own metabolic capacities according to their belonging to different groups of individuals defined on the basis of the similarity of their metabolic capacities. Due to different life trajectories, inter-individual variability could be amplified upon entry into the aging period, which could explain at least in part why traditional strategies for managing chronic age-related pathologies are insufficient. The investigators aim is to propose a new strategy to better understand inter-individual variability in the response to food in the elderly based on deep phenotyping.
Trial Details
NCT Number NCT06163794
Lead Sponsor Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Conditions
(from sponsor)		 Non Dependant 60 to 75 Year-old Men and Women
Related terms Motor Activity
Enrollment 250 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov