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Cabozantinib With Ifosfamide in Relapsed/Refractory Sarcomas

StatusRecruiting
PhasePhase 1
Started
View on ClinicalTrials.gov ↗

Record History

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  1. Minor Site contacts updated at 1 of 4 sitesv8
  2. Minor Secondary endpoints: 4 to 5v7 Show 4 more changesShow less
    • Study description shortened, about 12 words
    • Site details revised at 2 of 4 sites
    • Eligibility criteria shortened, about 2 words
    • Study title shortened, about 2 words
  3. Minor Re-verified, no change to tracked fieldsv6
  4. Minor Site contacts updated at 1 of 4 sitesv5
  5. Minor Site details revised at 2 of 4 sitesv4
Show 2 earlier versionsHide 2 earlier versions
  1. Minor Study sites: 5 to 4
    • Collaborators reordered
    v3
  2. Minor Secondary endpoints: details revised at 1 of 4 entries
    • Eligibility criteria shortened, about 2 words
    v2
  1. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The purpose of this study is to better understand how safe and effective the drug cabozantinib in combination with high-dose ifosfamide is in the treatment of children and adults with relapsed/refractory sarcomas.
Trial Details
NCT Number NCT06156410
Lead Sponsor Children's Hospital of Philadelphia
Collaborators: Children's Hospital Colorado, Alex's Lemonade Stand Foundation, Exelixis
Conditions
(from sponsor)
Ewing Sarcoma, Osteosarcoma, Sarcomas
Related terms Osteosarcoma, Recurrence, Sarcoma, Sarcoma, Ewing
Enrollment 30 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov