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Neoadjuvant Chemotherapy for Obstructive Colon cancER First Treated by cOlostomy

Study acronym: COnCERTO
StatusRecruiting
PhasePhase 3
Started2024-05-07
View on ClinicalTrials.gov ↗

Amendment history

2026-02-05
notable
Not Yet Recruiting→Recruiting Study Status, Contacts/Locations v2
Trial statusNot Yet Recruiting→Recruiting
Primary completion date2032-01→2031-08
Completion date2032-01→2031-08
Start dateestimated 2025-01→confirmed 2024-05-07
Study sites0→28
2024-06-26
minor
Study Status v1
Primary completion date2031-01→2032-01
Completion date2031-01→2032-01
Start date2024-01→2025-01
2023-10-25
minor
Original filing
The aim of this study is to determine whether chemotherapy prior to tumor removal (neoadjuvant chemotherapy), in patients undergoing treatment for colon cancer in occlusion (CCO), would improve the rate of patients able to benefit from "optimal" treatment, i.e. complete treatment (including all neoadjuvant and adjuvant chemotherapy cures). This new strategy, which would combine chemotherapy before surgery and possibly post-operatively (depending on tumor analysis), could improve the prognosis of occluded colon cancers by treating circulating micrometastases and/or inducing a reduction in tumor size, thereby increasing the rate of complete resection.
Trial Details
NCT Number NCT06107920
Lead Sponsor University Hospital, Rouen
Conditions Colon Cancer
Enrollment 232 participants
Start Date 2024-05-07
Primary Completion 2031-08 (estimated)
Study Completion 2031-08 (estimated)
Updated on ClinicalTrials.gov 2026-02-10