Clinical Trial

Neoadjuvant Chemotherapy for Obstructive Colon cancER First Treated by cOlostomy

Study acronym: COnCERTO
Recruiting Phase 3
View on ClinicalTrials.gov →
Summary
The aim of this study is to determine whether chemotherapy prior to tumor removal (neoadjuvant chemotherapy), in patients undergoing treatment for colon cancer in occlusion (CCO), would improve the rate of patients able to benefit from "optimal" treatment, i.e. complete treatment (including all neoadjuvant and adjuvant chemotherapy cures). This new strategy, which would combine chemotherapy before surgery and possibly post-operatively (depending on tumor analysis), could improve the prognosis of occluded colon cancers by treating circulating micrometastases and/or inducing a reduction in tumor size, thereby increasing the rate of complete resection.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2023-10-25; most recent amendment 2026-02-05.
Status change: Not Yet Recruiting → Recruiting 2026-02-05
Trial Details
NCT Number NCT06107920
Lead Sponsor University Hospital, Rouen
Conditions Colon Cancer
Enrollment 232 participants
Start Date 2024-05-07
Primary Completion 2031-08 (estimated)
Study Completion 2031-08 (estimated)
Updated on ClinicalTrials.gov 2026-02-10