Clinical Trial

Dosing of LT4 in Older Individuals

Name: Dosing of LT4 in Older Individuals — clinical trial record (NCT06073665)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Study acronym: DOT4

Recruiting Phase 4

View on ClinicalTrials.gov →

Summary

Our overall goal is to determine the clinical consequences of allowing greater flexibility in LT4 dosing in older individuals who take LT4.

Protocol Amendment History 5 amendments

This ClinicalTrials.gov record has been amended 5 times since 2023-10-02; most recent amendment 2026-02-17.

Status change: Not Yet Recruiting → Recruiting 2024-02-21

Trial Details

NCT Number	NCT06073665
Lead Sponsor	University of Pennsylvania Collaborators: National Institute on Aging (NIA)
Conditions	Hypothyroidism
Enrollment	228 participants
Start Date	2024-01-31
Primary Completion	2028-04-01 (estimated)
Study Completion	2028-04-01 (estimated)
Updated on ClinicalTrials.gov	2026-02-19