Clinical Trial

NAC vs Placebo on Opioid Use for Hysterectomy

Recruiting Phase 3
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Summary
This study will enroll females who are ages 18 and older undergoing a laparoscopic or robotic, partial or full hysterectomy. Participants will be randomized to receive IV n-acetylcysteine or placebo during the first 60 minutes of their procedure. At various time points after the procedure patients will be asked to report their pain scores, and any pain medication taken.
Protocol Amendment History 4 amendments
This ClinicalTrials.gov record has been amended 4 times since 2023-09-08; most recent amendment 2025-10-10.
Status change: Not Yet Recruiting → Recruiting 2023-12-01
Trial Details
NCT Number NCT06039566
Lead Sponsor Medical University of South Carolina
Conditions Hysterectomy
Enrollment 240 participants
Start Date 2023-11-30
Primary Completion 2026-11-25 (estimated)
Study Completion 2026-12-09 (estimated)
Updated on ClinicalTrials.gov 2025-10-14