Image-Based, In-Vivo Assessment of Tumor Hypoxia to Guide Hypoxia-Driven Adaptive Radiation Therapy

This study will apply novel MRI approaches with established sensitivity to tissue oxygen consumption and perfusion to predict hypoxia-associated radiation resistance, manifested as tumor recurrence and progression post-treatment.

NCT Number	NCT05996432
Lead Sponsor	Vanderbilt-Ingram Cancer Center Collaborators: National Institutes of Health (NIH)
Conditions	Head and Neck Squamous Cell Carcinoma, Brain Metastases
Enrollment	48 participants
Start Date	2023-05-17
Primary Completion	2026-11-30 (estimated)
Study Completion	2029-05-31 (estimated)
Updated on ClinicalTrials.gov	2024-09-23