Clinical Trial

Peptide Vaccine To Prevent Acquired Resistance In Patients With Advanced ALK+ NSCLC

Study acronym: ARCHER
Recruiting Phase 1/2
View on ClinicalTrials.gov →
Summary
The purpose of this study is to evaluate the safety of a cancer peptide vaccine to prevent or delay acquired resistance in advanced ALK+ lung cancer patients currently on ALK targeted therapy.
Protocol Amendment History 1 change
notable Primary completion pushed: 2026-07 -> 2027-07 2026-07-29
Trial Details
NCT Number NCT05950139
Lead Sponsor Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Collaborators: Oncovir, Inc.
Conditions NSCLC Stage IV, ALK Fusion Protein Expression
Enrollment 12 participants
Start Date 2024-05-13
Primary Completion 2027-07 (estimated)
Study Completion 2029-07 (estimated)
Updated on ClinicalTrials.gov 2026-07-28