Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT05933681 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

Neurophysiology Biomarkers of Cognitive Impairment Associated With Deep Brain Stimulation

StatusActive, Not Recruiting
PhaseNot applicable
Started2023-07-06
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 11 months later Aug 2026 → Aug 2027
See other at-risk trials from Vanderbilt University Medical Center

Amendment history

2026-09-22
Primary completion pushed: 2026-08 → 2027-08
Completion pushed: 2027-05 → 2027-08
2026-06-10
Study Status v10
Primary completion date2025-07-30→2026-08
Completion date2026-05-30→2027-05
2025-12-05
Study Status, Oversight v9
Completion date2025-10-30→2026-05-30
2025-10-20
Recruiting→Active, Not Recruiting Study Status, Contacts/Locations v8
Trial statusRecruiting→Active, Not Recruiting
Study sitesdetails revised at 1 of 1 site
2025-08-20
Study Status, Oversight, Contacts/Locations v7
Re-verified, no change to tracked fields
Show 6 earlier versions
2025-08-06
Study Status, Oversight, Contacts/Locations v6
Primary completion dateestimated 2025-06-30→confirmed 2025-07-30
Completion date2025-06-30→2025-10-30
Study sitescontacts updated at 1 of 1 site
2025-03-18
Study Status, Oversight, Contacts/Locations v5
Re-verified, no change to tracked fields
2025-01-21
Study Status, Contacts/Locations v4
Study sitescontacts updated at 1 of 1 site
2024-07-25
Study Status, Study Design v3
Re-verified, no change to tracked fields
2024-07-24
Study Status, Sponsor/Collaborators, Contacts/Locations v2
Collaborators+35 characters
United States Department of Defense
2023-07-21
Study Status, Study Design v1
Start dateestimated 2023-07-01→confirmed 2023-07-06
2023-06-27
Original filing
The study aims to investigate cognitive impairment associated with Deep Brain Stimulation (DBS) in Parkinson's Disease patients, with a focus on identifying neurophysiology biomarkers of DBS associated cognitive changes. Using neurophysiology data recorded during DBS surgeries and post-implantation, the research intends to identify biomarkers in order to optimize electrode placement, enhance programming, and ultimately minimize DBS-related cognitive side effects.
Trial Details
NCT Number NCT05933681
Lead Sponsor Vanderbilt University Medical Center
Collaborators: United States Department of Defense
Conditions Parkinson Disease
Enrollment 160 participants
Start Date 2023-07-06
Primary Completion 2027-08 (estimated)
Study Completion 2027-08 (estimated)
Updated on ClinicalTrials.gov 2026-09-21