Clinical Trial

TMS-fNIRS Personalized Dosing

Recruiting
View on ClinicalTrials.gov →
Record status
This record was last updated March 18, 2026 (before its estimated June 30, 2026 completion). Its status may not reflect the trial's current state.
Summary
The intent of this study is to establish technical feasibility in a clinical population (PTSD, with or without mild TBI) of personalized TMS-fNIRS technology. Thereby demonstrating the utility of transcranial magnetic stimulation - functional near-infrared spectroscopy (TMS-fNIRS) technology as a direct measure of frontal brain activity, potentially replacing the indirect motor threshold procedure that may lead to improper dosing of TMS. Personalized TMS-fNIRS technology will guide therapy for depression, post-traumatic stress disorder (PTSD), and/or traumatic brain injury (TBI)
Protocol Amendment History 5 amendments
This ClinicalTrials.gov record has been amended 5 times since 2023-06-14; most recent amendment 2026-03-16.
Status change: Not Yet Recruiting → Recruiting 2024-02-13
Trial Details
NCT Number NCT05916417
Lead Sponsor Florida State University
Conditions Post Traumatic Stress Disorder, Traumatic Brain Injury
Enrollment 60 participants
Start Date 2024-01-19
Primary Completion 2026-06-30 (estimated)
Study Completion 2026-09-30 (estimated)
Updated on ClinicalTrials.gov 2026-03-18