Clinical Trial

A Study of AK104 With Chemotherapy as First-line Treatment in Patients With Advanced Pancreatic Cancer

Recruiting Phase 2
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Record status
This record was last updated December 16, 2024 (before its estimated June 2025 completion). Its status may not reflect the trial's current state.
Summary
This study is a multicenter, open-label, phase II study to evaluate the safety, tolerability, pharmacokinetics (PK), immunogenicity, pharmacodynamics (PD) and anti-tumor activities of AK104,a PD-1/CTLA-4 bispecific antibody, in combination with chemotherapy as first-line therapy in subjects with advanced unresectable or metastatic pancreatic ductal adenocarcinoma.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2023-05-05.
Status change: Not Yet Recruiting → Recruiting 2024-12-11
Trial Details
NCT Number NCT05859750
Lead Sponsor Akeso
Conditions Pancreatic Cancer
Enrollment 78 participants
Start Date 2023-05-25
Primary Completion 2025-06 (estimated)
Study Completion 2025-12 (estimated)
Updated on ClinicalTrials.gov 2024-12-16