Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT05813327 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

Neoadjuvant ADI-PEG 20 + Ifosfamide + Radiotherapy in Soft Tissue Sarcoma

Name: Neoadjuvant ADI-PEG 20 + Ifosfamide + Radiotherapy in Soft Tissue Sarcoma — clinical trial record (NCT05813327)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

StatusTerminated

PhasePhase 1

SponsorWashington University School of Medicine

Started2024-03-14

View on ClinicalTrials.gov ↗

In this study, patients with soft tissue sarcoma (STS) will receive ADI-PEG 20 and ifosfamide in combination with radiation as neoadjuvant therapy. In phase I of the study, up to 5 dose levels will be tested to find the recommended phase II dose (RP2D), after which patients enrolling to phase II will be treated at that dose level to assess efficacy.

Amendment history 2 changes detected by DataLookout

2026-09-04

Trial terminated: Polaris decided to close to accrual.

2026-04-21

Completion moved earlier: 2028-05-31 → 2026-07-22

Trial Details

NCT Number	NCT05813327
Lead Sponsor	Washington University School of Medicine Collaborators: Polaris Group
Conditions	Soft Tissue Sarcoma, Sts, Sarcoma,Soft Tissue
Enrollment	6 participants
Start Date	2024-03-14
Primary Completion	2026-04-10 (estimated)
Study Completion	2026-07-22 (estimated)
Updated on ClinicalTrials.gov	2026-09-03