Study of Comparing of With and Without Sequential Therapy of S-1

The goal of this single arm clinical trial is to learn about sequential S-1 adjuvant therapy in patient wich locally advanced gastric cancer. The main question it aims to answer is: • The efficacy and safety of S-1 adjuvant therapy, following D2 radical surgery and DS(Docetaxel + S-1) adjuvant chemotherapy. All patients with locally advanced gastric cancer will received D2 radical surgery, 6 cycles of DS chemotherapy, and sequential S-1 chemotherapy up to 1 year postoperation.

NCT Number	NCT05813015
Lead Sponsor	Zhejiang University
Conditions	Locally Advanced Gastric Adenocarcinoma, Chemotherapy Effect
Enrollment	70 participants
Start Date	2023-01-28
Primary Completion	2026-12-31 (estimated)
Study Completion	2026-12-31 (estimated)
Updated on ClinicalTrials.gov	2023-04-14