Postoperation Maintenance Therapy for Resectable Liver Metastases of Colorectal Cancer Guided by ctDNA

The goal of this clinical trial is to compare in resectable liver metastases colorectal cancer patients.The main question it aims to answer is to investigate whether the progression-free survival (PFS) of resectable colorectal liver metastasis (CRLM) patients with positive ctDNA after surgery is superior with the combination of adjuvant chemotherapy and maintenance therapy compared to adjuvant chemotherapy alone.

NCT Number	NCT05797077
Lead Sponsor	Sixth Affiliated Hospital, Sun Yat-sen University
Conditions	Colorectal Cancer, Liver Metastases, Circulating Tumor Cell, Cancer, Therapy-Related
Enrollment	346 participants
Start Date	2023-02-20
Primary Completion	2029-02-20 (estimated)
Study Completion	2031-02-20 (estimated)
Updated on ClinicalTrials.gov	2023-04-04