Clinical Trial

ctDNA in CRC Patients Undergoing Curative-intent Surgery for Liver Metastases

Study acronym: CLIMES
Recruiting
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Record status
This record was last updated July 23, 2025 (before its estimated September 25, 2025 completion). Its status may not reflect the trial's current state.
Summary
This is a prospective multicenter cohort study, was designed to explore the prognostic value of ctDNA as a biomarker of disease response and recurrence or death in patients undergoing curative-intent surgical resection of Colorectal cancer liver metastasis.
Protocol Amendment History 5 amendments
This ClinicalTrials.gov record has been amended 5 times since 2023-03-24; most recent amendment 2025-07-22.
Status change: Not Yet Recruiting → Recruiting 2024-02-02
Trial Details
NCT Number NCT05787197
Lead Sponsor GERCOR - Multidisciplinary Oncology Cooperative Group
Conditions Metastatic Colorectal Cancer, Circulating Tumor DNA
Enrollment 232 participants
Start Date 2024-01-09
Primary Completion 2025-09-25 (estimated)
Study Completion 2027-06-30 (estimated)
Updated on ClinicalTrials.gov 2025-07-23