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NCT05766579 · ClinicalTrials.gov record · last posted 2026-07-02

Comparison Trial Between Elastic-compressive Stockings at 21 Versus 32 mmHg

Study acronym: CALESSE
StatusActive, Not Recruiting
PhaseNot applicable
Started2019-04-02
View on ClinicalTrials.gov ↗
from the ClinicalTrials.gov record
Endovascular thermal ablation is currently considered as the best procedure for treating varicose veins thanks to its mini-invasiveness and the lowest rate of incidence of complications. At the end of the endovascular ablation procedure, the European Society of Vascular Surgery (ESVS) guidelines recommend the use of the compression stockings to reduce postoperative pain and the incidence of edema and thrombotic complications. Despite this, the duration, type and degree of compression to be used, particularly after radiofrequency ablation procedures, remain a matter of debate. Furthermore, although the benefits of postoperative elastic compression therapy are well known, there is various evidence demonstrating how patients often experience poor comfort in wearing stockings, especially those with a higher degree of compression, which causes poor compliance with therapy. In light of all this, each center recommends the use of elastic compression stockings in the postoperative period with a degree of compression that varies, however, according to internal protocols. There is currently no work in the literature that compares the advantages and disadvantages of using elastic compression stockings with a K2 versus K1 compression degree after radiofrequency ablative surgery.

Amendment record 3 amendments on the ClinicalTrials.gov record

This ClinicalTrials.gov record has been amended 3 times since 2023-03-10; most recent amendment 2026-07-01. DataLookout shows field-level changes from the day a trial enters its daily monitoring; earlier amendments are counted here from the ClinicalTrials.gov version history. See every version on ClinicalTrials.gov ↗

2026-07-01
Status change RecruitingActive, Not Recruitingv3
Trial Details
NCT Number NCT05766579
Lead Sponsor IRCCS Policlinico S. Donato
Conditions Vascular Surgical Procedures
Enrollment 64 participants
Start Date 2019-04-02
Primary Completion 2026-12-30 (estimated)
Study Completion 2026-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-07-02