Clinical Trial

The Effect of Subclinical Leaflet Thrombosis and Prosthesis Type on Transcatheter Aortic Valve Degeneration (POPular PET TAVI)

Recruiting
View on ClinicalTrials.gov →
Summary
A multicentre cross-sectional cohort study to assess the difference in bioprosthetic micro-calcification activity, detected with 18F-NaF PET-CT, as early marker of transcatheter valve degeneration, between patients with vs. without subclinical leaflet thrombosis at five years after TAVI; and between patients with intra-annular vs. supra-annular TAVI prostheses.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2023-02-24; most recent amendment 2026-05-18.
Status change: Not Yet Recruiting → Recruiting 2024-04-08
Trial Details
NCT Number NCT05758662
Lead Sponsor St. Antonius Hospital
Collaborators: St. Antonius Research Fund, Medtronic
Conditions Aortic Valve Stenosis
Enrollment 180 participants
Start Date 2023-11-16
Primary Completion 2026-10-01 (estimated)
Study Completion 2026-10-01 (estimated)
Updated on ClinicalTrials.gov 2026-05-19