2024-01-30
minor
Study Identification, Study Status, Sponsor/Collaborators, Outcome Measures, Eligibility, IPDSharing v5
Completion date2028-03-30→2026-03-30
Start date2024-01-01→2024-02
Eligibility criteria+52 characters
[...] angiography (MRA)
Onset of ischemic stroke within 24 hours and able to get baseline pMRI within 72 hours of onsetarrival
4) NIH Stroke Scale ≥6 4 at time of enrollment
Exclusion Criteria:
Pre-morbid mRS ≥3 [...]
Secondary endpoints4 to 9 entries
RecurrentIncidence of stroke
RecurrentIncidence of stroke
Change in Montreal Cognitive declineAssessment scale (MoCA-BLIND) to assess post-stroke cognition
CognitiveChange declinein Oral Trails A and B Test to assess post-stroke cognition
Change in Category Fluency tests to assess post-stroke cognition
Change in Patient Health Questionnaire (PHQ-9) to assess mood
Change in General Anxiety Disorder-7 (GAD-7) to assess mood
Change in Lawton Instrumental Activities of Daily Liv [...]
Collaborators2 to 3 entries
National Institute of Neurological Disorders and Stroke (NINDS)
2023-03-20
minor
Study Status, Study Description, Outcome Measures v1
Secondary endpointsdetails revised at 2 of 4 entries
Study description+44 characters
[...] retrospective analyses, independent of mean blood pressure.
OurThe investigators' central hypothesis is that increased BPV is harmful after A [...] ntihypertensive medications on BPV.
To achieve these goals, wethe study will enroll 150 patients who have anterior circulation stro [...] IS onset at three study sites.
With completion of the Aims, wethe study will define the outcome for a future trial, the effect size [...] ge of healthcare settings.
By completing the proposed aims, wethe investigators will be ideally positioned to test accessible targeted interventions to diminish the morbidity and mortality of AIS.