Clinical Trial

Fluorescence-guided Surgery in Laryngeal- and Hypopharyngeal Cancer: a Feasibility Trial

Study acronym: STELLAR
Not Yet Recruiting Phase 2
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Summary
This is an open-label, single-dose, prospective clinical trial. The study comprises 2 work packages. The main objective of work package I (WP-1) is to assess feasibility of Fluorescence imaing (FLI) during total laryngectomy (TLE) and to assess the optimal dose of the cRGD-ZW800-1. Work package II (WP-II) is designed to assess whether FLI can detect and decrease tumor positive margins after a TLE.
Protocol Amendment History 4 amendments
This ClinicalTrials.gov record has been amended 4 times since 2023-02-21; most recent amendment 2025-02-25.
Trial Details
NCT Number NCT05752149
Lead Sponsor Erasmus Medical Center
Conditions Squamous Cell Carcinoma of the Larynx, Squamous Cell Carcinoma of the Hypopharynx
Enrollment 27 participants
Start Date 2025-06-01
Primary Completion 2027-02-01 (estimated)
Study Completion 2027-03-01 (estimated)
Updated on ClinicalTrials.gov 2025-02-26