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Perioperative Chemotherapy Plus Toripalimab for dMMR Locally Advanced Gastric or Esophagogastric Junction Adenocarcinoma

Name: Perioperative Chemotherapy Plus Toripalimab for dMMR Locally Advanced Gastric or Esophagogastric Junction Adenocarcinoma — clinical trial record (NCT05729646)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

StatusRecruiting

PhasePhase 2

SponsorYu jiren

Started2023-05-31

View on ClinicalTrials.gov ↗

Record status

This record was last updated July 25, 2023 (before its estimated February 28, 2026 completion). Its status may not reflect the trial's current state.

Amendment history

2023-07-24

Not Yet Recruiting→Recruiting Study Status, Contacts/Locations v1

Trial statusNot Yet Recruiting→Recruiting

Start dateestimated 2023-02-28→confirmed 2023-05-31

Study sitesdetails revised at 8 of 8 sites

2023-02-07

Original filing

Yu jiren

5 trials monitored

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Gastric Cancer

1,194 trials monitored

See 60 trials at risk

This study is a prospective, multi-center, randomized controlled phase II trial to compare the efficacy of perioperative SOX plus toripalimab, toripalimab monotherapy with SOX regimen in participants with dMMR locally advanced gastric or esophagogastric junction adenocarcinoma

Trial Details

NCT Number	NCT05729646
Lead Sponsor	Yu jiren
Conditions	Adenocarcinoma of the Stomach, Adenocarcinoma of Esophagogastric Junction, Mismatch Repair Deficiency
Enrollment	90 participants
Start Date	2023-05-31
Primary Completion	2026-02-28 (estimated)
Study Completion	2029-02-28 (estimated)
Updated on ClinicalTrials.gov	2023-07-25