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PErsonalized TReatment for Endometrial Carcinoma

Study acronym: PETREC
StatusRecruiting
PhaseNot applicable
Started
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Record History

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  1. Minor Interventions: Comparison of adjuvant therapies (Other), Comparison of adjuvant therapies (Other) to Comparison of VBT vs. WPRT (Other), Comparison of chemotherapy vs. chemoradiotherapy (Other)
    • Collaborators revised (7)
    v2
  2. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The goal of this clinical trial is to compare the efficacy of adjuvant therapies in women with stage I-II molecular integrated high-intermediate or high-risk endometrial carcinoma. Specifically, the invesigators want to compare: * Chemotherapy vs. chemoradiotherapy in p53 abn subtype and nonendometrioid carcinomas. * Vaginal brachytherapy vs. whole pelvic radiotherapy in the MMR-D molecular subgroup. * Vaginal brachytherapy vs. whole pelvic radiotherapy in the NSMP molecular subgroup.
Trial Details
NCT Number NCT05655260
Lead Sponsor University of Helsinki
Collaborators: Turku University Hospital, Tampere University Hospital, Kuopio University Hospital, Oulu University Hospital, Kymenlaakso Central Hospital Kotka Finland, Päijänne Tavastia Central Hospital, South Carelia Central Hospital
Conditions
(from sponsor)
Endometrial Adenocarcinoma
Related terms Endometrial Neoplasms
Enrollment 300 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov