Clinical Trial

Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

Recruiting Phase 3
View on ClinicalTrials.gov →
Summary
The purpose of this study is to evaluate the efficacy and safety of tebentafusp-based regimens, including tebentafusp monotherapy and in combination with anti-PD1 vs investigator choice (including clinical trials of investigational agents, salvage therapy per local standard of care \[SoC\], best supportive care \[BSC\] on protocol survivor follow up) in patients with advanced non-ocular melanoma.
Protocol Amendment History 9 amendments
This ClinicalTrials.gov record has been amended 9 times since 2022-09-19; most recent amendment 2026-02-23.
Status change: Not Yet Recruiting → Recruiting 2023-02-21
Trial Details
NCT Number NCT05549297
Lead Sponsor Immunocore Ltd
Conditions Advanced Melanoma
Enrollment 540 participants
Start Date 2022-12-19
Primary Completion 2028-03 (estimated)
Study Completion 2028-07 (estimated)
Updated on ClinicalTrials.gov 2026-02-25