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rTMS for Military TBI-related Depression

Study acronym: ADEPT
StatusRecruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Record status
This record was last updated April 29, 2026 (before its estimated September 30, 2026 completion). Its status may not reflect the trial's current state.

Record History

See every version on ClinicalTrials.gov ↗

  1. Site details revised at 1 of 3 sitesv7
  2. Trial status: Not Yet Recruiting to Recruiting
    • Start date changed from estimate of Jun 1, 2024 to Dec 16, 2024
    • Site details revised at 3 of 3 sites
    v6
  3. Eligibility criteria expanded, about 8 words
    • Study description expanded, about 7 words
    • Collaborators: 1 to 2
    v5
  4. Enrollment target: 1 to 198v4 Show 8 more changesShow less
    • Primary completion date: Sep 23, 2022 to Sep 30, 2026
    • Start date: Aug 17, 2022 to Jun 1, 2024
    • Trial status: Active, Not Recruiting to Not Yet Recruiting
    • Study sites: 2 to 3
    • Study completion date: Jan 1, 2023 to Dec 31, 2026
    • Eligibility criteria shortened, about 26 words
    • Study description expanded, about 14 words
    • Study arms: 16 to 3
  5. Enrollment target: estimated 440 to confirmed 1v3 Show 4 more changesShow less
    • Trial status: Recruiting to Active, Not Recruiting
    • Primary completion date changed from estimate of Aug 1, 2026 to Sep 23, 2022
    • Study completion date: Apr 1, 2027 to Jan 1, 2023
    • Site details revised at 2 of 2 sites
  6. Trial status: Not Yet Recruiting to Recruitingv2 Show 5 more changesShow less
    • Primary completion date: Jan 2026 to Aug 1, 2026
    • Primary endpoints revised (6)
    • Study sites: 0 to 2
    • Study completion date: Aug 2026 to Apr 1, 2027
    • Start date changed from estimate of Jul 2022 to Aug 17, 2022
  7. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The purpose of this study is to investigate the efficacy, safety, and tolerability of two dorsolateral prefrontal cortex (DLPFC) repetitive transcranial magnetic stimulation (rTMS) protocols to alleviate symptoms of depression in United States (U.S.) military service members and veterans with a history of concussion/mild traumatic brain injury (TBI).
Trial Details
NCT Number NCT05426967
Lead Sponsor Henry M. Jackson Foundation for the Advancement of Military Medicine
Collaborators: Uniformed Services University of the Health Sciences, Congressionally Directed Medical Research Programs
Conditions
(from sponsor)		 Depressive Symptoms, Mild Traumatic Brain Injury, Concussion
Related terms Brain Concussion, Depression
Enrollment 198 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov