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Role of Glucose Metabolism in Migration of Cutaneous Dendritic Cells in Psoriasis

StatusRecruiting
PhaseNot applicable
Started2022-06-30
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 13 months later Jun 1, 2026 → Jul 1, 2027
See other at-risk trials from Centre Hospitalier Universitaire de Nice

Amendment history

2026-10-02
Primary completion pushed: 2026-06-01 → 2027-07-01
Completion pushed: 2026-09-01 → 2028-09-01
2024-10-14
2 amendments v2-v3
2 re-verifications since 2023-09-05, no change to tracked fields
2022-06-30
Not Yet Recruiting→Recruiting Study Status, Contacts/Locations v1
Trial statusNot Yet Recruiting→Recruiting
Start dateestimated 2022-06-01→confirmed 2022-06-30
Study sitesdetails revised at 1 of 1 site
2022-05-30
Original filing
Dendritic cells (DC) paly a key role in the induction and chronicity of psoriasis by capturing the antigenes and activating the T cell repsonse. This activation requires their migration from the cutaneous sensitisation site to the lymph nodes. This migration requires an important intracellular metabolic activity, with a strong involvmenet of glucdic metabolism. This activity is linked with the systemic activity. This study aims to compare the migration and the phenotypic and metabolic caracteristics of blood and skin DCs in patients with or without psoriasis and with or without type 2 diabetes,
Trial Details
NCT Number NCT05399433
Lead Sponsor Centre Hospitalier Universitaire de Nice
Conditions Psoriasis
Enrollment 100 participants
Start Date 2022-06-30
Primary Completion 2027-07-01 (estimated)
Study Completion 2028-09-01 (estimated)
Updated on ClinicalTrials.gov 2026-10-01