Clinical Trial

Sodium Lowering Vascular Effects Trial

Study acronym: SOLVE
Recruiting
View on ClinicalTrials.gov →
Summary
The proposed mechanistic trial will test the effect of dietary sodium reduction on cardiac and vascular structure and function in those with elevated blood pressure or hypertension. Findings from this study will fill the knowledge gap on the underlying mechanisms of dietary sodium intake on cardiovascular disease risk in addition to blood pressure and could provide further evidence on sodium reduction for the prevention of cardiovascular disease.
Protocol Amendment History 6 amendments
This ClinicalTrials.gov record has been amended 6 times since 2022-05-19; most recent amendment 2024-11-20.
Status change: Not Yet Recruiting → Recruiting 2023-03-01
Trial Details
NCT Number NCT05388032
Lead Sponsor Tulane University
Collaborators: Johns Hopkins University
Conditions Endothelial Dysfunction, Vascular Stiffness, Left Ventricular Hypertrophy, Left Ventricular Dysfunction
Enrollment 256 participants
Start Date 2023-01-25
Primary Completion 2026-12-31 (estimated)
Study Completion 2026-12-31 (estimated)
Updated on ClinicalTrials.gov 2024-11-22