Clinical Trial

Safety and Tolerability of the Use of Copaiba in Patients With Oral Cancer Submitted to Radiotherapy

Active, Not Recruiting Phase 1
View on ClinicalTrials.gov →
Summary
This study aims to propose an alternative and auxiliary methodology for the prevention and treatment of Oral Mucositis (OM) in patients undergoing radiotherapy or radio and chemotherapy for head and neck neoplasms through the use of copaiba-based mouthwash, since the treatment that currently has proven efficacy for the prevention of OM(Low Power Laser Therapy) cannot be applied in tumor regions due to the risk of stimulating the tissue proliferation of malignant cells.
Protocol Amendment History 1 change
notable Enrollment reduced: 36 -> 20 participants 2026-05-02
Trial Details
NCT Number NCT05308732
Lead Sponsor Instituto Nacional de Cancer, Brazil
Conditions Head and Neck Neoplasms, Mucositis Oral, Radiotherapy; Complications
Enrollment 20 participants
Start Date 2021-05-11
Primary Completion 2025-09-07 (estimated)
Study Completion 2026-12 (estimated)
Updated on ClinicalTrials.gov 2026-05-01