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Sex Disparities in Hypoxic Vasodilation and Impact of Obesity

StatusRecruiting
PhaseEarly Phase 1
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 1 year 1 month later Jun 30, 2026 → Jul 30, 2027
See other at-risk trials from University of Missouri-Columbia

Record History

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  1. Primary and study completion pushed from Jun 30, 2026 to Jul 30, 2027v9
  2. Primary and study completion dates: Jul 2026 to Jun 30, 2026v8
  3. Primary and study completion dates: Jul 2025 to Jul 2026
    • Site contact updated
    v7
  4. Eligibility criteria shortened, about 8 wordsv6
  5. Trial status: Not Yet Recruiting to Recruiting
    • Start date changed from estimate of Feb 2023 to Mar 14, 2023
    • Interventions: Acetylcholine (Drug), Isoproterenol (Drug), Norepinephrine (Drug), Propranolol Hydrochloride (Drug), Sodium Nitroprusside (Drug) to Isoproterenol (Drug), Norepinephrine (Drug), Phentolamine Mesylate (Drug), Propranolol Hydrochloride (Drug)
    • Site details revised
    v5
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  1. Start date: Jun 2022 to Feb 2023v4
  2. Start date: Feb 2022 to Jun 2022v3
  3. Re-verified, no change to tracked fieldsv2
  1. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The purpose of this project is to examine key mechanisms contributing to sex-differences in hypoxic vasodilation and the impact of obesity, with particular emphasis on the sympathetic nervous system.
Trial Details
NCT Number NCT05219799
Lead Sponsor University of Missouri-Columbia
Conditions
(from sponsor)		 Obesity, Vasodilation, Healthy
Related terms Aneurysm, Obesity
Enrollment 72 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov