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NCT05212272 · ClinicalTrials.gov record · last posted 2026-08-17

MRI in High-Grade Glioma Patients Undergoing Chemoradiation

StatusRecruiting
PhaseNot applicable
Started2022-09-02
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from the ClinicalTrials.gov record
The purpose of this research study is to see if investigators can predict how brain functioning changes after radiation treatment based on PET scans and blood tests. Most participants experience at least mild decreases in their memory or attention after radiation therapy. Investigators hope that PET scans, optional lumbar puncture, and blood tests might help investigators predict who might have larger changes in their brain function after radiation.

Protocol amendment history 2 changes detected by DataLookout

2026-08-18
critical
Primary completion pushed: 2026-12 → 2027-12
2026-08-18
minor
Completion pushed: 2026-12 → 2027-12
Trial Details
NCT Number NCT05212272
Lead Sponsor Wake Forest University Health Sciences
Collaborators: National Cancer Institute (NCI)
Conditions High Grade Glioma
Enrollment 16 participants
Start Date 2022-09-02
Primary Completion 2027-12 (estimated)
Study Completion 2027-12 (estimated)
Updated on ClinicalTrials.gov 2026-08-17