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Combination of Pembrolizumab and Cabozantinib in Patients With Advanced Sarcomas

Study acronym: PEMBROCABOSARC
StatusRecruiting
PhasePhase 2
Started
View on ClinicalTrials.gov ↗

Record History

See every version on ClinicalTrials.gov ↗

  1. Primary completion date: Apr 28, 2024 to Dec 2026
    • Study completion date: Oct 31, 2025 to Dec 2027
    v6
  2. Site details revised at 1 of 10 sites
    • Eligibility criteria expanded, about 4 words
    v5
  3. Site details revised at 4 of 10 sitesv4
  4. Trial status: Not Yet Recruiting to Recruitingv3 Show 4 more changesShow less
    • Primary completion date: Feb 28, 2024 to Apr 28, 2024
    • Study completion date: Aug 31, 2025 to Oct 31, 2025
    • Start date changed from estimate of Feb 28, 2022 to Apr 25, 2022
    • Site details revised at 10 of 10 sites
  5. Start date: Dec 31, 2021 to Feb 28, 2022
    • Primary completion date: Dec 31, 2023 to Feb 28, 2024
    • Study completion date: Jun 30, 2024 to Aug 31, 2025
    • Eligibility criteria shortened, about 1 word
    v2
  6. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Institut Bergonié
40 trials monitored
See 1 trial at risk
Sarcoma
1,026 trials monitored
See 67 trials at risk
Phase II trial with three independent strata to independently assess the effects of the association of pembrolizumab and cabozantinib in advanced sarcomas.
Trial Details
NCT Number NCT05182164
Lead Sponsor Institut Bergonié
Collaborators: Ipsen, MSD France
Conditions
(from sponsor)		 Soft Tissue Sarcoma Adult, Advanced Soft-tissue Sarcoma, Ewing Sarcoma, Osteosarcoma, Undifferentiated Pleomorphic Sarcoma
Related terms Histiocytoma, Malignant Fibrous, Osteosarcoma, Sarcoma, Sarcoma, Ewing
Enrollment 119 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov