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Non-invasive Brain Mapping of Movement Facilitation in Parkinson's Disease

StatusActive, Not Recruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗

Record History

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  1. Study completion pushed from Sep 2026 to Sep 2027
    • Primary completion date changed from estimate of Sep 2026 to Sep 1, 2026
    • Eligibility criteria expanded, about 5 words
  2. Trial status: Recruiting to Active, Not Recruiting
    • Site details revised
    v5
  3. 2 versions Re-verified since Dec 15, 2023, no change to tracked fieldsv3-v4
  4. Start date changed from estimate of Feb 2022 to Jul 6, 2022v2
  5. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Several strategies or contexts help patients with Parkinson's disease to move more quickly or normally, however the brain mechanisms underlying these phenomena are poorly understood. The proposed studies use complimentary brain mapping techniques to understand the brain mechanisms supporting improved movements elicited by external cues. The central hypothesis is that distinct networks are involved in movement improvement depending on characteristics of the facilitating stimulus. Participants will perform movement tasks during recording of brain activity with EEG and MRI. The identified biomarkers may provide targets for future neuromodulation therapies to improve symptoms that are refractory to current treatments, such as freezing of gait.
Trial Details
NCT Number NCT05179187
Lead Sponsor University of California, Los Angeles
Collaborators: National Institute of Neurological Disorders and Stroke (NINDS)
Conditions
(from sponsor)		 Parkinson Disease
Related terms Parkinson Disease
Enrollment 90 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov