Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT05141513 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

Intraoperative Radiation Therapy After Stereotactic Body Radiation Therapy and Chemotherapy in Treatment of Pancreatic Adenocarcinoma

StatusActive, Not Recruiting
PhasePhase 1
Started2022-05-06
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Enrollment reduced 20% 25 → 20 participants
See other at-risk trials from Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Amendment history

2026-09-19
Primary completion confirmed: July 2025 (last estimated July 2026)
2026-07-31
Study Status, Study Design, Contacts/Locations v9
Enrollment closed, study ongoing
Enrollment reduced: 25 → 20 participants
Study sitesdetails revised at 1 of 1 site
2025-07-17
Study Status, Eligibility v8
Primary completion date2025-06→2026-07
Eligibility criteriarevised
[...] ve fertile men with partners who are women of child bearing potenitalpotential who are unwilling or unable to use an acceptable method to avoid pregnancy for the entire study
2024-07-12
Study Status v7
Primary completion date2024-06→2025-06
2024-02-13
Study Status v6
Primary completion date2023-12→2024-06
Show 5 earlier versions
2023-06-28
Study Status v5
Primary completion date2023-04→2023-12
2022-06-03
Not Yet Recruiting→Recruiting Study Status, Contacts/Locations v4
Trial statusNot Yet Recruiting→Recruiting
Start dateestimated 2022-04→confirmed 2022-05-06
Study sitesdetails revised at 1 of 1 site
2022-03-18
Study Status v3
Primary completion date2023-02→2023-04
Completion date2028-02→2028-04
Start date2022-02→2022-04
2022-02-07
Study Identification, Study Status v2
Re-verified, no change to tracked fields
2022-01-26
Study Status v1
Primary completion date2023-12→2023-02
Completion date2028-12→2028-02
Start date2021-12→2022-02
2021-11-23
Original filing
This study is designed to investigate the safety of intraoperative radiation therapy (IORT) in patients with localized pancreatic cancer undergoing surgical resection after neoadjuvant chemotherapy and stereotactic body radiation therapy (SBRT).
Trial Details
NCT Number NCT05141513
Lead Sponsor Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Conditions Pancreatic Cancer
Enrollment 20 participants
Start Date 2022-05-06
Primary Completion 2025-07-02 (estimated)
Study Completion 2028-04 (estimated)
Updated on ClinicalTrials.gov 2026-09-18