Clinical Trial

Intraoperative Radiation Therapy After Stereotactic Body Radiation Therapy and Chemotherapy in Treatment of Pancreatic Adenocarcinoma

Active, Not Recruiting Phase 1
View on ClinicalTrials.gov →
Summary
This study is designed to investigate the safety of intraoperative radiation therapy (IORT) in patients with localized pancreatic cancer undergoing surgical resection after neoadjuvant chemotherapy and stereotactic body radiation therapy (SBRT).
Protocol Amendment History 2 changes
critical Enrollment closed, study ongoing 2026-08-04
notable Enrollment reduced: 25 -> 20 participants 2026-08-04
Trial Details
NCT Number NCT05141513
Lead Sponsor Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Conditions Pancreatic Cancer
Enrollment 20 participants
Start Date 2022-05-06
Primary Completion 2026-07 (estimated)
Study Completion 2028-04 (estimated)
Updated on ClinicalTrials.gov 2026-08-03