Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT05136703 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

Treatment Research Investigating Depression Effects on Neuroimmune Targets (TRIDENT)

Study acronym: TRIDENT
StatusRecruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗

Record History

See every version on ClinicalTrials.gov ↗

  1. Primary completion date: Dec 31, 2026 to Jun 30, 2027
    • Study completion date: Jul 31, 2027 to Dec 31, 2027
    v16
  2. Primary completion date: Sep 30, 2026 to Dec 31, 2026
    • Eligibility criteria expanded, about 14 words
    • Site contacts updated at 1 of 2 sites
    v15
  3. Primary completion date: Dec 31, 2025 to Sep 30, 2026
    • Study completion date: Jul 31, 2026 to Jul 31, 2027
    • Site contacts updated at 1 of 2 sites
    v14
  4. Study sites: 1 to 2
    • Eligibility criteria revised
    v13
  5. Primary completion date: Jun 30, 2025 to Dec 31, 2025
    • Study completion date: Oct 31, 2025 to Jul 31, 2026
    v12
Show 10 earlier versionsHide 10 earlier versions
  1. Eligibility criteria shortened, about 8 wordsv11
  2. Site contact updatedv10
  3. Eligibility criteria expanded, about 9 wordsv9
  4. Lead sponsor: University of Miami to Florida International Universityv8
  5. Eligibility criteria revised
    • Secondary endpoints revised (7)
    v7
  6. Start date changed from estimate of Sep 15, 2022 to Aug 30, 2022v6
  7. Start date: Jun 15, 2022 to Sep 15, 2022v5
  8. Trial status: Not Yet Recruiting to Recruitingv4 Show 4 more changesShow less
    • Primary completion date: Mar 1, 2024 to Jun 30, 2025
    • Study completion date: Mar 1, 2024 to Oct 31, 2025
    • Start date changed from estimate of Sep 1, 2022 to Jun 15, 2022
    • Site details revised
  9. Start date: Jun 1, 2022 to Sep 1, 2022v3
  10. Start date: Mar 1, 2022 to Jun 1, 2022
    • Secondary endpoints: details revised at 4 of 7 entries
    • Study description expanded, about 163 words
    v2
  1. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The purpose of this randomized controlled trial is to understand how a cognitive-behavioral treatment (a form of psychological treatment) for depression changes the gut microbiome (micro-organisms that regulate the health of the gut), immune system, and the brain functioning in people living with HIV.
Trial Details
NCT Number NCT05136703
Lead Sponsor Florida International University
Collaborators: National Institute of Mental Health (NIMH)
Conditions
(from sponsor)		 Depression, HIV-1-infection, Inflammation
Related terms Depression, Inflammation
Enrollment 150 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov