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An Optimal Dose Finding Study of N-Acetylcysteine in Patients With Myeloproliferative Neoplasms

StatusRecruiting
PhasePhase 1/2
Started
View on ClinicalTrials.gov ↗

Record History

  1. Notable Primary completion date: Jul 31, 2025 to Nov 15, 2026v7
  2. Minor Site contacts updated at 1 of 2 sitesv6
  3. Notable Trial status: Active, Not Recruiting to Recruiting Primary completion date: Jul 31, 2024 to Jul 31, 2025 · Study sites: 1 to 2 · Completion date: Nov 15, 2025 to Nov 15, 2026v5 Show 3 more changesShow less
    • Primary completion date: Jul 31, 2024 to Jul 31, 2025
    • Study sites: 1 to 2
    • Completion date: Nov 15, 2025 to Nov 15, 2026
  4. Notable Primary completion date: Nov 15, 2022 to Jul 31, 2024v4
  5. Minor Trial status: Recruiting to Active, Not Recruiting Site details revisedv3 Show 1 more changeShow less
    • Site details revised
  6. Notable Trial status: Not Yet Recruiting to Recruiting Start date changed from estimate of Nov 15, 2021 to Jan 3, 2022 · Site details revisedv2 Show 2 more changesShow less
    • Start date changed from estimate of Nov 15, 2021 to Jan 3, 2022
    • Site details revised
  7. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This is a phase I/II study evaluating the optimal dose of N-acetylcysteine (N-AC) in patients with myeloproliferative neoplasms (MPN).
Trial Details
NCT Number NCT05123365
Lead Sponsor University of California, Irvine
Conditions Myeloproliferative Neoplasm, MPN, Essential Thrombocythemia, Polycythemia Vera, Myelofibrosis
Enrollment 27 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov