Pencil Beam Proton Therapy for Recurrences in Anal Cancer Patients Previously Treated With Radiotherapy (DACG 5)

This protocol aims to determine toxicity and efficacy of re-irradiation for patients with recurrences from anal cancers with dose-escalated pencil beam proton therapy either pre-operative for marginally resectable recurrences or as a definitive treatment strategy (un-resectable, operation declined etc.). The over-all aim is to improve local tumor control with acceptable side effects.

NCT Number	NCT05055635
Lead Sponsor	University of Aarhus
Conditions	Anal Cancer, Recurrent Anal Cancer
Enrollment	55 participants
Start Date	2021-07-07
Primary Completion	2027-07-06 (estimated)
Study Completion	2030-07-06 (estimated)
Updated on ClinicalTrials.gov	2021-09-24