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Cardiovascular Manifestations of MR Activation in Primary Aldosteronism: Pilot Clinical Study

StatusRecruiting
PhasePhase 4
Started2022-12-15
View on ClinicalTrials.gov ↗

Amendment history

2025-02-05
minor
Study Status v2
Re-verified, no change to tracked fields
2023-02-24
notable
Not Yet Recruiting→Recruiting Study Status, Contacts/Locations v1
Trial statusNot Yet Recruiting→Recruiting
Primary completion date2026-09→2026-10-31
Completion date2026-09→2027-02-28
Start dateestimated 2021-10→confirmed 2022-12-15
Study sites0→1
2021-08-26
minor
Original filing
This research study aims to learn more about the impact the hormone aldosterone on the heart. Primary aldosteronism is a condition where the body's adrenal glands make too much of the hormone aldosterone, which can cause high blood pressure and increase the risk of heart and kidney disease. Treatment with medications that block aldosterone can reduce that risk. This study is trying to learn whether treatment with a medication that blocks aldosterone can improve heart function in people who make too much aldosterone.
Trial Details
NCT Number NCT05030545
Lead Sponsor Brigham and Women's Hospital
Conditions Primary Aldosteronism, Hypertension
Enrollment 40 participants
Start Date 2022-12-15
Primary Completion 2026-10-31 (estimated)
Study Completion 2027-02-28 (estimated)
Updated on ClinicalTrials.gov 2025-02-07