Cardiovascular Manifestations of MR Activation in Primary Aldosteronism: Pilot Clinical Study

This research study aims to learn more about the impact the hormone aldosterone on the heart. Primary aldosteronism is a condition where the body's adrenal glands make too much of the hormone aldosterone, which can cause high blood pressure and increase the risk of heart and kidney disease. Treatment with medications that block aldosterone can reduce that risk. This study is trying to learn whether treatment with a medication that blocks aldosterone can improve heart function in people who make too much aldosterone.

NCT Number	NCT05030545
Lead Sponsor	Brigham and Women's Hospital
Conditions	Primary Aldosteronism, Hypertension
Enrollment	40 participants
Start Date	2022-12-15
Primary Completion	2026-10-31 (estimated)
Study Completion	2027-02-28 (estimated)
Updated on ClinicalTrials.gov	2025-02-07