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A Study of AK104 Plus Platinum-containing Chemotherapy±Bevacizumab as First-line Treatment for Persistent, Recurrent, or Metastatic Cervical Cancer

StatusActive, Not Recruiting
PhasePhase 3
SponsorAkeso
Started2021-08-27
View on ClinicalTrials.gov ↗
Record status
This record was last updated November 19, 2025 (before its estimated December 30, 2025 completion). Its status may not reflect the trial's current state.

Amendment history

2025-11-17
minor
Study Status v3
Primary completion date2025-04-01→2025-12-30
2025-02-28
notable
Recruiting→Active, Not Recruiting Study Status, Study Design, Contacts/Locations, References v2
Trial statusRecruiting→Active, Not Recruiting
Enrollment targetestimated 440→confirmed 445
Study sitesdetails revised at 5 of 5 sites
2022-04-26
notable
Not Yet Recruiting→Recruiting Study Status, Contacts/Locations v1
Trial statusNot Yet Recruiting→Recruiting
Start dateestimated 2021-07-30→confirmed 2021-08-27
Study sites7→5
2021-07-21
minor
Original filing
96 trials monitored
See 1 trial at risk
853 trials monitored
See 46 trials at risk
This is A Randomized, Double-blind, Placebo-controlled Phase III Study to Evaluate AK104 Plus Platinum-containing Chemotherapy With or Without Bevacizumab as First-line Treatment for Persistent, Recurrent, or Metastatic Cervical Cancer
Trial Details
NCT Number NCT04982237
Lead Sponsor Akeso
Conditions Cervical Cancer
Enrollment 445 participants
Start Date 2021-08-27
Primary Completion 2025-12-30 (estimated)
Study Completion 2025-12-30 (estimated)
Updated on ClinicalTrials.gov 2025-11-19