Catheter-Related Early Thromboprophylaxis With Enoxaparin Studies

The goal of the CRETE Studies is to investigate the newly identified age-dependent heterogeneity in the efficacy of enoxaparin in reducing the risk of central venous catheter-associated deep venous thrombosis in critically ill children.

NCT Number	NCT04924322
Lead Sponsor	Yale University Collaborators: Children's Hospital Colorado, Children's Hospital of Philadelphia, BJC HealthCare, Medical College of Wisconsin, Children's of Alabama, Golisano Children's Hospital, Maria Fareri Children's Hospital, Nationwide Children's Hospital, New York Presbyterian Hospital, Penn State University, University of Iowa, Johns Hopkins All Children's Hospital, University of Oklahoma, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), Children's Hospital of Illinois at Peoria, Hassenfeld Children's Hospital
Conditions	Deep Venous Thrombosis
Enrollment	258 participants
Start Date	2022-05-11
Primary Completion	2027-04-30 (estimated)
Study Completion	2027-08-31 (estimated)
Updated on ClinicalTrials.gov	2026-06-08