Clinical Trial

DIStal gastriC Bypass OUtcome in Revision SurgEry After Roux-en-y Gastric Bypass

Study acronym: DISCOURSE
Recruiting
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Summary
This study is designed as a prospective multicenter randomized controlled clinical trial comparing two surgical techniques of distal gastric bypass (DGB) in revisional surgery following failed Roux-en-Y gastric bypass. Patients will be randomly allocated 1:1 to A) DGB with lengthening of the BPL (DGB type I) or B) DGB with extended AL (DGB type II). Randomisation is stratified for participating center. The study will be performed in a clinical and out-patient setting with regular visits at 1.5, 3, 6, 12, 18, 24 and 36 months post intervention. The study will be set up as a multicenter study with bariatric centers: St. Antonius hospital, Groene Hart hospital, OLVG, Rijnstate hospital, Elisabeth Twee-steden Hospital, Bravis hospital, Medisch Centrum Leeuwarden, Catharina Hospital.
Protocol Amendment History 4 amendments
This ClinicalTrials.gov record has been amended 4 times since 2021-05-16; most recent amendment 2026-04-24.
Status change: Not Yet Recruiting → Recruiting 2021-06-01
Trial Details
NCT Number NCT04894838
Lead Sponsor St. Antonius Hospital
Collaborators: Medtronic
Conditions Obesity, Morbid, Weight Gain
Enrollment 150 participants
Start Date 2021-05-01
Primary Completion 2029-09 (estimated)
Study Completion 2029-12 (estimated)
Updated on ClinicalTrials.gov 2026-04-27