Clinical Trial

ELEVATE, a Registry of Patients With Acute Hepatic Porphyria (AHP)

Study acronym: ELEVATE
Recruiting
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Summary
This global patient registry is being conducted to characterize the natural history and real-world clinical management of patients with AHP, and to further characterize the real-world safety and effectiveness of givosiran and other approved AHP therapies.
Protocol Amendment History 52 amendments
This ClinicalTrials.gov record has been amended 52 times since 2021-05-07; most recent amendment 2026-04-23.
Trial Details
NCT Number NCT04883905
Lead Sponsor Alnylam Pharmaceuticals
Conditions Acute Hepatic Porphyria
Enrollment 150 participants
Start Date 2021-04-26
Primary Completion 2027-04-01 (estimated)
Study Completion 2027-04-01 (estimated)
Updated on ClinicalTrials.gov 2026-04-27