Modifying Progesterone and Estradiol Levels to Prevent Postpartum Cigarette Smoking Relapse and Reduce Secondhand Smoke Exposure in Infants and Children

The investigators aim to address the following specific aims: * Determine the efficacy of Prog in preventing postpartum smoking relapse and reducing smoking relapse risk factors. * Examine the effects of this maternal smoking intervention on infant health. * Examine racial and ethnic differences in intervention outcomes.

NCT Number	NCT04783857
Lead Sponsor	University of Minnesota Collaborators: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Conditions	Smoking, Smoking Cessation, Smoking Reduction
Enrollment	171 participants
Start Date	2022-04-14
Primary Completion	2027-06-02 (estimated)
Study Completion	2027-06-02 (estimated)
Updated on ClinicalTrials.gov	2026-06-04