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Study of Pelvic Hypofractionated Radiotherapy in Endometrial Cancer

StatusSuspended
PhasePhase 1/2
Started2021-01-15
View on ClinicalTrials.gov ↗
This study will investigate if a shorter treatment course (known as "hypofractionation") for pelvic radiation is safe for women with endometrial cancer. Doctors leading the study will also determine the safest and most tolerable dose of shortened radiation (hypofractionation) used to treat women in this study. Because this study will shorten the radiation course typically used to treat endometrial cancer, each daily treatment given to women in this study will be slightly higher than normal to ensure that the total radiation dose they receive is still effective and similar to the radiation dose they would receive if they were not participating in this study (standard treatment).

Amendment history 3 changes detected by DataLookout

2026-09-11
Recruitment suspended: Enrollment Goal Met
2026-09-11
Completion moved earlier: 2027-05-22 → 2026-12-20
2026-09-04
Primary completion confirmed: August 2026 (last estimated May 2027)
Trial Details
NCT Number NCT04683653
Lead Sponsor University of Chicago
Conditions Endometrial Cancer
Enrollment 100 participants
Start Date 2021-01-15
Primary Completion 2026-08-20 (estimated)
Study Completion 2026-12-20 (estimated)
Updated on ClinicalTrials.gov 2026-09-10