Trial statusNot Yet Recruiting→Recruiting
Primary completion date2022-09-30→2026-06-30
Completion date2022-12-31→2027-04-01
Start dateestimated 2021-02-01→confirmed 2023-02-04
Study sites0→1
Eligibility criteria+385 characters
Inclusion Criteria:
Aged ≥40 years
Newly diagnosed COPD patients with postPost-bronchodilator FEV1/FVC <70% or previously diagnosed of COPD by physicians and confirmed by PFT.
Baseline COPD Assessment Test (CAT) score ≥10 or history of exacerbation in previous 12 months, defined as any use of oral antibiotics and/or oral or nebulized corticosteroids for increased cough, sputum and dyspnea, or exacerbation requiring hospitalization/ emergency admission.
Local residents who willlive nearby and can be accessiblefollowed and available for follow-up duringthroughout trialstudy period
Written inform [...] [...]
Secondary endpoints1 to 8 entries
EffectiveExacerbation assessmentsevents
Hospital forreadmissions
Hospital secondarystay
Healthcare outcomescost
Lung function change
Symptom change
Patients' care-seeking behaviors
Patients' adherence to treatment
Primary endpoints1 entry, revised
Annual rate of moderate and severe COPD exacerbationsEffectiveness
Study description-49 characters
COPD is the most common chronic respiratory disease in China and has caused significant economic and disease burden.
An effective and standardized condition management strategy is urgently needed to reduce the incidence ofprevent acute exacerbation, improve the quality of patients' life, and avoid premature death causeddue byto COPD.
At present,COPD management of COPD is mainly conductedperformed in community-level health institutions.
Implementing COPD standardized management of COPD in primary care will help improve the level of COPD prevention and treatment in China.
WeThe investigators wil [...] [...]
Publications1 to 4 entries
Khakban A, Sin DD, FitzGerald JM, McManus BM, Ng R, Hollander Z, Sadatsafavi M. The Projected Epidemic of Chronic Obstructive Pulmonary Disease Hospitalizations over the Next 15 Years. A Population-based Perspective. Am J Respir Crit Care Med. 2017 Feb 1;195(3):287-291. doi: 10.1164/rccm.201606-1162 [...]