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Brain Stimulation for Improving Cognition in Chronic Stroke (NEPTUNE)

Study acronym: NEPTUNE
StatusActive, Not Recruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 5 months later Jul 30, 2026 → Dec 30, 2026
See other at-risk trials from Medical University of South Carolina

Record History

  1. Primary endpoints: details revised at 1 of 3 entries Primary and study completion pushed from Jul 30, 2026 to Dec 30, 2026 · Eligibility criteria expanded, about 12 words · Publications: details revised at 1 of 1 entry Show 3 more changesShow less
    • Primary and study completion pushed from Jul 30, 2026 to Dec 30, 2026
    • Eligibility criteria expanded, about 12 words
    • Publications: details revised at 1 of 1 entry
  2. Primary and study completion pushed from May 15, 2026 to Jul 30, 2026v18
  3. Primary completion pushed from Mar 15, 2026 to May 15, 2026v17
  4. Primary completion date: Dec 15, 2025 to Mar 15, 2026 Completion date: Dec 15, 2025 to May 15, 2026v16 Show 1 more changeShow less
    • Completion date: Dec 15, 2025 to May 15, 2026
  5. Primary and study completion dates: Oct 30, 2025 to Dec 15, 2025v15
Show 13 earlier versionsHide 13 earlier versions
  1. Primary and study completion dates: May 30, 2025 to Oct 30, 2025v14
  2. Primary and study completion dates: Dec 30, 2024 to May 30, 2025v13
  3. Primary and study completion dates: Dec 30, 2023 to Dec 30, 2024v12
  4. Primary completion date: Jun 30, 2023 to Dec 30, 2023 Trial status: Recruiting to Active, Not Recruiting · Enrollment target: estimated 40 to confirmed 20 · Completion date: Sep 1, 2023 to Dec 30, 2023 · 1 morev11 Show 4 more changesShow less
    • Trial status: Recruiting to Active, Not Recruiting
    • Enrollment target: estimated 40 to confirmed 20
    • Completion date: Sep 1, 2023 to Dec 30, 2023
    • Site details revised
  5. Primary completion date: Jun 30, 2022 to Jun 30, 2023 Completion date: Sep 1, 2022 to Sep 1, 2023v10 Show 1 more changeShow less
    • Completion date: Sep 1, 2022 to Sep 1, 2023
  6. Primary completion date: Feb 2022 to Jun 30, 2022 Completion date: Apr 1, 2022 to Sep 1, 2022v9 Show 1 more changeShow less
    • Completion date: Apr 1, 2022 to Sep 1, 2022
  7. Primary completion date: Oct 2021 to Feb 2022 Completion date: Mar 1, 2022 to Apr 1, 2022v8 Show 1 more changeShow less
    • Completion date: Mar 1, 2022 to Apr 1, 2022
  8. Completion date: Oct 2021 to Mar 1, 2022v7
  9. Primary and study completion dates: Jun 20, 2021 to Oct 2021v6
  10. Primary and study completion dates: Mar 31, 2021 to Jun 20, 2021v5
  11. Primary and study completion dates: Jul 31, 2021 to Mar 31, 2021 Start date changed from estimate of Jan 2021 to Jan 14, 2021v4 Show 1 more changeShow less
    • Start date changed from estimate of Jan 2021 to Jan 14, 2021
  12. Start date: Dec 7, 2020 to Jan 2021v3
  13. Primary endpoints revised (3)v2 See this version in full on ClinicalTrials.gov ↗
  1. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Few treatments are available for post-stroke rehabilitation. The current study aims to develop a novel, short-term, high-dose repetitive transcranial magnetic stimulation (rTMS) based intervention to improve post-stroke cognitive problems. This study will test the safety as well as changes in cognitive function and brain activation with the administration of an accelerated rTMS protocol in chronic stroke.
Trial Details
NCT Number NCT04655963
Lead Sponsor Medical University of South Carolina
Collaborators: National Institutes of Health (NIH), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Conditions Chronic Stroke
Enrollment 20 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov