Clinical Trial

Prophylactic Preoperative HIPEC in Advanced Gastric Cancer at High Risk of Peritoneal Recurrence

Study acronym: CHIMERA
Recruiting Phase 3
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Record status
This record was last updated March 6, 2024 (before its estimated January 2026 completion). Its status may not reflect the trial's current state.
Summary
The study was designed to evaluate the efficacy of perioperative FLOT chemotherapy in combination with perioperative hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with advanced gastric cancer at high risk of peritoneal metastases. The impact of treatment on peritoneal recurrence and survival over 6 months, 1, 3 and 5 years will be assessed.
Protocol Amendment History 8 amendments
This ClinicalTrials.gov record has been amended 8 times since 2020-10-20; most recent amendment 2024-03-04.
Status change: Not Yet Recruiting → Recruiting 2021-08-23
Trial Details
NCT Number NCT04597294
Lead Sponsor Jagiellonian University
Conditions Gastric Cancer
Enrollment 600 participants
Start Date 2021-08-01
Primary Completion 2026-01 (estimated)
Study Completion 2026-12 (estimated)
Updated on ClinicalTrials.gov 2024-03-06