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A Study of Polatuzumab Vedotin, Rituximab and Dose Attenuated CHP in Older Patients With DLBCL

StatusActive, Not Recruiting
PhasePhase 2
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 12 months later Jul 31, 2026 → Jul 31, 2027
See other at-risk trials from University of Rochester

Record History

See every version on ClinicalTrials.gov ↗

  1. Notable Primary and study completion pushed from Jul 31, 2026 to Jul 31, 2027
    • Eligibility criteria expanded, about 36 words
  2. Minor Trial status: Recruiting to Active, Not Recruiting
    • Site details revised
    v9
  3. Notable Primary and study completion dates: Jul 31, 2024 to Jul 31, 2026v8
  4. Minor 3 versions Re-verified since Jan 6, 2022, no change to tracked fieldsv5-v7
  5. Notable Trial status: Not Yet Recruiting to Recruiting
    • Study sites: 0 to 1
    • Start date: Oct 31, 2021 to Sep 20, 2021
    v4
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  1. Notable Start date: Jul 2, 2021 to Oct 31, 2021v3
  2. Notable Start date: Jan 2, 2021 to Jul 2, 2021v2
  1. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The purpose of this study is to test the effectiveness and safety of polatuzumab vedotin in combination with R-miniCHP in patients 75 years and older with DLBCL.
Trial Details
NCT Number NCT04594798
Lead Sponsor University of Rochester
Collaborators: Genentech, Inc.
Conditions
(from sponsor)
DLBCL, Lymphoma, B-Cell
Related terms Lymphoma, B-Cell
Enrollment 39 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov