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NCT04567771 · ClinicalTrials.gov record · last posted 2026-08-19

Comparison of Proton or Intensity Modulated Radiation Therapy After Surgery for Endometrial or Cervical Cancer

StatusRecruiting
PhaseNot applicable
Started2020-12-04
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from the ClinicalTrials.gov record
This early phase I trial compares the side effects between patients treated with proton radiation therapy versus intensity modulated radiation therapy after surgery for the treatment of endometrial or cervical cancer. Radiation therapy uses high energy protons or x-rays to kill tumor cells and shrink tumors. Using quality of life questionnaires and adverse event assessments may help doctors learn whether proton radiation therapy is associated with lower acute gastrointestinal toxicities at the end of treatment compared to intensity modulated radiation therapy in patients with endometrial or cervical cancer.

Protocol amendment history 4 changes detected by DataLookout

2026-08-20
notable
Enrollment reopened
2026-06-23
notable
Primary completion pushed: 2028-10-15 → 2029-04-01
2026-06-23
minor
Completion pushed: 2028-10-15 → 2029-04-01
2026-06-13
notable
Trial status changed: Recruiting → Active, Not Recruiting
Trial Details
NCT Number NCT04567771
Lead Sponsor Mayo Clinic
Conditions Cervical Carcinoma, Endometrial Carcinoma, Endometriosis, Pelvic Inflammatory Disease
Enrollment 121 participants
Start Date 2020-12-04
Primary Completion 2029-04-01 (estimated)
Study Completion 2029-04-01 (estimated)
Updated on ClinicalTrials.gov 2026-08-19