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NCT04511845 · ClinicalTrials.gov record · last posted 2026-07-30

A Dose-Escalation Study of SPYK04 in Patients With Locally Advanced or Metastatic Solid Tumors (With Expansion).

StatusCompleted
PhasePhase 1
Started2020-09-10
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from the ClinicalTrials.gov record
Phase I, open-label, multi-center study

Protocol amendment history 4 changes detected by DataLookout

2026-07-31
Trial completed
2026-07-31
Enrollment reduced: 113 → 85 participants
2026-07-31
Primary completion moved earlier: 2026-09-30 → 2026-06-18
2026-07-31
Completion moved earlier: 2026-09-30 → 2026-06-18
Trial Details
NCT Number NCT04511845
Lead Sponsor Chugai Pharmaceutical
Conditions Locally Advanced or Metastatic Solid Tumors
Enrollment 85 participants
Start Date 2020-09-10
Primary Completion 2026-06-18 (estimated)
Study Completion 2026-06-18 (estimated)
Updated on ClinicalTrials.gov 2026-07-30