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NotablePrimary endpoints revised (5)v67Show 4 more changesShow less
Study sites: 50 to 51
Eligibility criteria expanded, about 841 words
Study description shortened, about 6 words
Study title revised
MinorSite contacts updated at 1 of 50 sitesv66
MinorSite contacts updated at 1 of 50 sitesv65
MinorSite contacts updated at 1 of 50 sitesv64
MinorStudy sites: 49 to 50v63
MinorStudy sites: 50 to 49v62
MinorSite contacts updated at 1 of 50 sitesv61
MinorStudy sites: 51 to 50v60
MinorStudy sites: 50 to 51v59
MinorSite details revised at 3 of 50 sitesv58
MinorSite details revised at 1 of 50 sitesv57
MinorSite details revised at 1 of 50 sitesv56
MinorSite details revised at 1 of 50 sitesv55
MinorStudy sites: 49 to 50v54
MinorSite details revised at 2 of 49 sitesv53
MinorSite details revised at 1 of 49 sitesv52
MinorSite details revised at 1 of 49 sitesv51
MinorSite contacts updated at 31 of 49 sitesv50
MinorSite details revised at 2 of 49 sitesv49
MinorSite contacts updated at 1 of 49 sitesv48
MinorSite details revised at 4 of 49 sitesv47
MinorSite details revised at 1 of 49 sitesv46
MinorSite details revised at 1 of 49 sitesv45
MinorSite contacts updated at 1 of 49 sitesv44
MinorSite contacts updated at 1 of 49 sitesv43
MinorSite details revised at 2 of 49 sitesv42
MinorSite contacts updated at 1 of 49 sitesv41
MinorSite details revised at 1 of 49 sitesv40
MinorSite contacts updated at 1 of 49 sitesv39
MinorSite details revised at 2 of 49 sitesv38
MinorSite contacts updated at 1 of 49 sitesv37
MinorSite contacts updated at 1 of 49 sitesv36
MinorSite contacts updated at 1 of 49 sitesv35
MinorSite details revised at 1 of 49 sitesv34
MinorSite details revised at 2 of 49 sitesv33
MinorSite details revised at 1 of 49 sitesv32
MinorSite details revised at 2 of 49 sitesv31
Stopped: an ongoing trial was terminated, suspended or withdrawn.
Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The Parkinson Progression Marker Initiative (PPMI) is a longitudinal, observational, multi-center natural history study to assess progression of clinical features, digital outcomes, and imaging, biologic and genetic markers of Parkinson's disease (PD) progression in study participants with manifest PD, prodromal PD, and healthy controls.
The overall goal of PPMI is to identify markers of disease progression for use in clinical trials of therapies to reduce progression of PD disability.