Clinical Trial

The IMmunotherapy Pleural 5-ALA PDT

Study acronym: IMPALA
Recruiting Phase 2
View on ClinicalTrials.gov →
Record status
This record was last updated September 25, 2025 (before its estimated May 9, 2026 completion). Its status may not reflect the trial's current state.
Summary
Pilot study of the feasibility of an innovative multimodal treatment combining intrapleural photodynamic therapy with videothoracoscopy followed by adjuvant immunotherapy with anti-PD-1 Nivolumab antibodies in patients with malignant pleural mesothelioma
Protocol Amendment History 5 amendments
This ClinicalTrials.gov record has been amended 5 times since 2020-05-20; most recent amendment 2025-09-24.
Status change: Not Yet Recruiting → Recruiting 2022-05-17
Trial Details
NCT Number NCT04400539
Lead Sponsor University Hospital, Lille
Collaborators: INSERM U1189 ONCOTHAI
Conditions Mesotheliomas Pleural, Malignant Pleural Mesothelioma
Enrollment 20 participants
Start Date 2022-05-09
Primary Completion 2026-05-09 (estimated)
Study Completion 2026-05-09 (estimated)
Updated on ClinicalTrials.gov 2025-09-25