Clinical Trial

A Randomized Controlled Trial Evaluating of Prophylactic Irradiation in CRT for cT1bN0M0 ESCC

Study acronym: ARMADILLO
Recruiting Phase 3
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Summary
This study is conducted to investigate whether modified chemoradiotherapy with elective nodal irradiation reduces the locoregional recurrence that cannot be completely resected by salvage endoscopic resection and preserve esophagus without compromising overall survival.
Protocol Amendment History 5 amendments
This ClinicalTrials.gov record has been amended 5 times since 2020-03-29; most recent amendment 2025-05-19.
Status change: Not Yet Recruiting → Recruiting 2020-09-08
Trial Details
NCT Number NCT04328948
Lead Sponsor National Cancer Center, Japan
Conditions Esophageal Squamous Cell Carcinoma
Enrollment 280 participants
Start Date 2020-07-01
Primary Completion 2030-03-31 (estimated)
Study Completion 2030-03-31 (estimated)
Updated on ClinicalTrials.gov 2025-05-22