Clinical Trial

Water-based Activity to Enhance Recall in Veterans

Study acronym: WATER-Vet
Active, Not Recruiting Phase 4
View on ClinicalTrials.gov →
Record status
This record was last updated August 17, 2025 (before its estimated March 31, 2026 completion). Its status may not reflect the trial's current state.
Summary
This four-year study will evaluate the efficacy of an exercise training augmentation for cognitive training intervention to improve memory performance in Veterans with a diagnosis of amnestic Mild Cognitive Impairment (aMCI). This is a two-phased trial: 1) an exercise phase and 2) a cognitive training program. The exercise phase will be an aquatic based exercise program. A combination of exercise and cognitive training programs designed for persons without cognitive impairment have significantly improved memory more than other single intervention groups (exercise only, cognitive training only) and given the success of combination training programs with healthy older adults, it is important to adapt these programs for persons beginning to exhibit clinically significant memory problems, such as those with aMCI.
Protocol Amendment History 9 amendments
This ClinicalTrials.gov record has been amended 9 times since 2020-03-02; most recent amendment 2025-08-15.
Status change: Recruiting → Active, Not Recruiting 2025-05-21
Status change: Not Yet Recruiting → Recruiting 2022-01-19
Trial Details
NCT Number NCT04296565
Lead Sponsor VA Office of Research and Development
Conditions Mild Cognitive Impairment
Enrollment 121 participants
Start Date 2022-01-03
Primary Completion 2026-03-31 (estimated)
Study Completion 2026-06-30 (estimated)
Updated on ClinicalTrials.gov 2025-08-17